This Review has been updated 13 times since it was first published in October of 2016. Biting insects aren’t just an uncomfortable irritant for cats and dogs; they can transmit some pretty nasty diseases to both animals and humans alike. The good news is that you can provide a strong defense against pests by applying one of these flea and tick sprays to a pet’s coat. Made with natural ingredients, they’ll prevent unwanted passengers from hitching a ride on your furry friend. When users buy our independently chosen editorial selections, we may earn commissions to help fund the Wiki. Review to the best flea and tick spray on Amazon.
10. Terra Pet Naturals
Unlike some topical options made from water and alcohol, Terra Pet Naturals boasts a blend of essential oils and apple cider vinegar, keeping toxic and potentially-harmful chemicals off your furry friend, while helping to nourish coats at the same time.
- Helps to balance skin ph level
- Doesn’t contain any preservatives
- Not ideal for long-haired breeds
9. Frontline Treatment
Certified by the EPA and recommended by veterinarians, groomers, and informed pet owners alike, Frontline Treatment contains fipronil, a broad-spectrum insecticide that quickly disrupts the central nervous systems of pests, killing them before they can lay their eggs.
- Formula is waterproof
- Effects last for 30 days
- May cause temporary skin irritation
8. Adams Plus
Adams Plus is a powerful formula that utilizes an insect growth regulator to break the life cycles of fleas and ticks, eliminating adults, eggs, and larvae, while also preventing new infestations from developing for up to two months after applying it.
- Good for pups with allergies
- Bright blue and red bottle
- Has a very strong odor
7. VetriScience VetriRepel
If you’re looking for a non-pesticide alternative to conventional flea treatments, try VetriScience VetriRepel the next time you take your dog to the park. Consisting of sustainable Brazilian oils, it provides an invisible shield of protection.
- Also safe for cats
- No sticky residue
- Not effective against mosquitoes
6. Cedar Bug-Free
A light misting of Cedar Bug-Free is all that’s required to eliminate all kinds of irritating pests from your furry friend. Its strong aroma overwhelms an insect’s respiratory system, causing its spiracles to close off and eventually suffocate it.
- Spray nozzle is easy to adjust
- Good for carpets too
- Requires daily application
5. Dr. Killigan’s Six Feet Under
Concocted from a potent mix of clove and cottonseed oils, Dr. Killigan’s Six Feet Under is a fast-acting formula designed to kill all stages of a flea’s life cycle, while also eliminating a wide variety of other bugs on contact, such as ants, moths, and roaches.
- No harsh chemicals
- Safe to use around food
- Bottle is very bulky
4. Honeydew Pet Pleasant
Honeydew Pet Pleasant comes as a complete grooming kit that includes a dedicated insect repellent and an antimicrobial shampoo made with citronella and lemongrass, both of which work in tandem to deodorize and prevent pests from hitching a ride on your dog or cat.
- Good for dry and itchy skin
- Money-back guarantee
- 8 ounces in each bottle
3. Vet’s Best Flea Killer
Whether you’re dealing with an infestation or performing routine pest prevention around the house, a bottle of Vet’s Best Flea Killer is an all-in-one solution for tackling either situation. Gentle on canine skin, it can be applied to puppies as young as 3 months.
- Made with peppermint and clove
- Water-based non-staining formula
- Very affordable price
2. Yaya Organics Dog Whisperer
Made with plant-based essential oils, like cedarwood, peppermint, rosemary, and lemongrass, Yaya Organics Dog Whisperer provides a safe, hypoallergenic, and all-natural way to keep biting insects at bay, regardless of whether you’re in the backyard or out camping.
- No synthetic dyes or fragrances
- Can be sprayed on human skin
- Also repels black flies
1. Wonderside Natural
Whether it’s rubbed directly into a dog’s coat or applied to carpets, wood flooring, and furniture in your home, Wonderside Natural repels and kills fleas, ticks, and mosquitoes on contact, while helping to prevent the occurrence of reinfestation.
- Choice of 4 scents
- Concentrated cedar oil
- Eliminates eggs and larvae
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