This Review has been updated 8 times since it was first published in May of 2018. Seeing a feline friend scratching constantly while trying to get some relief from parasites is upsetting. If your cat is suffering, these flea treatments can eradicate the infestation and prevent it spreading to your home. Many get the job done within days or even hours. Be sure to consult your vet first and get the correct dosages, though, because they can cause health issues if misapplied. When users buy our independently chosen editorial picks, we may earn commissions to help fund the Review. Skip to the best flea treatment for cats on Amazon.
10. PetArmor FastCaps
Trying to hold an animal with one hand and apply a liquid using the other can be a sure way to end up with puncture wounds all over your limbs, which is why PetArmor FastCaps are so convenient. They’re small tablets that Fluffy takes orally — no wrestling required.
- Start working within an hour
- Can be hidden in food
- Pricier than comparable products
9. Pet Naturals of Vermont Repellent
Pet Naturals of Vermont Repellent keeps fleas, ticks, mosquitoes, and other creepy-crawlies at bay, thanks to its combination of lemongrass, cinnamon, castor and sesame oils. It’s not sticky when applied, so feel free to spray it liberally.
- Contains no synthetic chemicals
- Safe to use on bedding
- Requires frequent reapplication
8. Vectra for Cats Over 9lbs
Owners of large breeds should keep a box of Vectra for Cats Over 9lbs handy, as it’s a quick-drying formula that’s easy to apply. It’s not greasy after you put it on, either, so you won’t have to worry about accidentally getting it all over your hands and clothes.
- Applicator has an extension tube
- Good for outdoor pets
- May cause temporary hair loss
7. Elanco Animal Health Cheristin
Elanco Animal Health Cheristin is a once-a-month treatment, so you can forget about it for 30 days. And each dose remains effective for up to six weeks, so if you don’t remember to reapply at precisely the four-week mark, your feline will still be covered.
- Gentle applicator tip
- Can battle full infestations
- Odor is too strong for some
6. Sentry Capguard
Safe for use on felines from two to 25 pounds, Sentry Capguard can treat moderate infestations in young and full-grown pets. You can give it to animals once a day, but keep in mind it only eradicates adult fleas and should be combined with a preventative product.
- Small capsules are easy to crush
- Flavorless for picky cats
- Recommended by many veterinarians
5. Novartis Capstar
Online feline communities say Novartis Capstar is comparable to Comfortis, but it doesn’t require you to obtain a prescription. It’s safe for kittens as young as four weeks old, so if you take in a feral baby who happens to bring her own set of critters, this can help.
- Also approved for pregnant cats
- Kills adult fleas within 30 minutes
- Can be used on dogs too
4. Wondercide Spray
If the thought of rubbing harsh pesticides into your pet’s skin each month causes you to shudder, you can use Wondercide Spray instead. Made with natural ingredients, like rosemary and cedar, it can be applied all over your house in addition to the affected animal.
- Also repels ticks and mosquitoes
- Clove- and phenol-free
- Ph-balanced formula
3. Bayer Seresto Collar
The Bayer Seresto Collar remains active for eight months, meaning it will provide coverage for all of flea season, and then some. Should an animal get trapped while wearing this, it can easily force open the safety release mechanism to escape.
- Reflective clip for nighttime
- Water-resistant construction
- Good for pets who won’t take pills
2. Frontline Plus
In addition to fleas, Frontline Plus also eradicates lice, making it a good choice for households with children who may bring home that troublesome parasite. Its applicator is designed to promote precise use, helping you put it where you want and nowhere else.
- Safe for lactating cats
- Very effective in high tick areas
- Tolerated by finicky pets
1. Bayer Animal Health Advantage II
Bayer Animal Health Advantage II is an odorless solution, so you can still snuggle up to your fuzzy little buddy without him smelling like a petrochemical factory. In addition to eliminating existing pests, it also terminates eggs and larvae, breaking the life cycle.
- Kills on contact
- Available in four dosages
- Pet can be bathed 24 hours after use
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